The three-dimensional structure of antibodies

Continuous cultures of fused cells secreting antibody of predefined specificity

Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations

Pharmacy, Cell Biology, Immunology +11

The interpretation of protein structures: Estimation of static accessibility

B. Lee, F.M. Richards · Journal of Molecular Biology · 1971 · 5.9K citations

Life Sciences, Biochemistry, Biophysics +12

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution.

J. Deisenhofer · PubMed · 1981 · 1.4K citations

Life Sciences, Biochemistry, Biophysics +17

AN ANALYSIS OF THE SEQUENCES OF THE VARIABLE REGIONS OF BENCE JONES PROTEINS AND MYELOMA LIGHT CHAINS AND THEIR IMPLICATIONS FOR ANTIBODY COMPLEMENTARITY

Tai Te Wu, Elvin A. Kabat · The Journal of Experimental Medicine · 1970 · 1.3K citations · Full text

Life Sciences, Biochemistry, Immunology +17

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-.ANG. resolution

J. Deisenhofer · Biochemistry · 1981 · 1.3K citations

Life Sciences, Biochemistry, Molecular Biology +14