Acute tolerance associated with a single opiate administration: involvement of N-methyl-d-aspartate-dependent pain facilitatory systems

A METHOD FOR DETERMINING LOSS OF PAIN SENSATION

F. E. D'Amour, Donn L. Smith · Journal of Pharmacology and Experimental Therapeutics · 1941 · 3.2K citations

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Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801

Keith A. Trujillo, Huda Akil · Science · 1991 · 1.2K citations

Medicine, Neuroscience, Pharmacology +17

Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation

Li Chen, Li-Yen Mae Huang · Nature · 1992 · 965 citations

Medicine, Neurobiology, Neuroscience +14

Thermal hyperalgesia in association with the development of morphine tolerance in rats: roles of excitatory amino acid receptors and protein kinase C

J Mao, D.J. Mayer · Journal of Neuroscience · 1994 · 455 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Sustained potentiation of NMDA receptor-mediated glutamate responses through activation of protein kinase C by a μ opioid

Li Chen, Li-Yen Mae Huang Marine · Neuron · 1991 · 444 citations

Life Sciences, Neurobiology, Neuroscience +16