Phosphorylation of isocitrate dehydrogenase as a demonstration of enhanced sensitivity in covalent regulation

The determination of enzyme inhibitor constants

Martin Dixon · Biochemical Journal · 1953 · 4.1K citations · Full text

Life Sciences, Biochemistry, Biochemical Pharmacology +15

Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits^*

Daniel E. Koshland, George Némethy, D. Filmer · Biochemistry · 1966 · 3K citations

Life Sciences, Biochemistry, Biophysics +13

An amplified sensitivity arising from covalent modification in biological systems.

Albert Goldbeter, Daniel E. Koshland · Proceedings of the National Academy of Sciences · 1981 · 1.3K citations

Life Sciences, Biochemistry, Molecular Biology +15

Protein kinase activity associated with the avian sarcoma virus src gene product.

Marc S. Collett, Raymond L. Erikson · Proceedings of the National Academy of Sciences · 1978 · 1.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Purification and Properties of Rabbit Skeletal Muscle Adenosine 3',5'-Monophosphate-dependent Protein Kinases

Erwin M. Reimann, Donal A. Walsh, Edwin G. Krebs · Journal of Biological Chemistry · 1971 · 812 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7