Pathogenesis, clinical features, and treatment advances in mastocytosis

Gain-of-Function Mutations of c- <i>kit</i> in Human Gastrointestinal Stromal Tumors

Seiichi Hirota, Koji Isozaki, Y Moriyama et al. · Science · 1998 · 4.5K citations

Medicine, Genetics, Oncology +17

<i>PDGFRA</i> Activating Mutations in Gastrointestinal Stromal Tumors

Michael C. Heinrich, Christopher L. Corless, Anette Duensing et al. · Science · 2003 · 2.3K citations

Medicine, Genetics, Oncology +17

A Tyrosine Kinase Created by Fusion of the <i>PDGFRA</i> and <i>FIP1L1</i> Genes as a Therapeutic Target of Imatinib in Idiopathic Hypereosinophilic Syndrome

Jan Cools, Daniel J. DeAngelo, Jason Gotlib et al. · New England Journal of Medicine · 2003 · 1.7K citations · Full text

Life Sciences, Genetics, Hematology +15

Human proto‐oncogene c‐kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

Yosef Yarden, Wun-Jing Kuang, Teresa L. Yang‐Feng et al. · The EMBO Journal · 1987 · 1.6K citations · Full text

Life Sciences, Molecular Biology, Oncology +13

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

Krisztina M. Zsebo, David A. Williams, E N Geissler et al. · Cell · 1990 · 1.4K citations

Life Sciences, Cell Biology, Genetics +14