Synthesis of docosahexaenoic acid derivatives designed as novel PPARγ agonists and antidiabetic agents

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver et al. · Journal of Biological Chemistry · 1995 · 3.6K citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

High-field FT NMR application of Mosher's method. The absolute configurations of marine terpenoids

Ikuko I. Ohtani, Takenori Kusumi, Yoel Kashman et al. · Journal of the American Chemical Society · 1991 · 3.2K citations

Natural Sciences, Chemistry, Analytical Chemistry +5

A useful 12-I-5 triacetoxyperiodinane (the Dess-Martin periodinane) for the selective oxidation of primary or secondary alcohols and a variety of related 12-I-5 species

D. B. DESS, J. C. Martin · Journal of the American Chemical Society · 1991 · 2.1K citations

Natural Sciences, Chemistry, Mass Spectrometric Analysis +8

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

Robert T. Nolte, G. Bruce Wisely, Stefan Westin et al. · Nature · 1998 · 1.9K citations

Life Sciences, Biochemistry, Molecular Biology +12

Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension

Inês Barroso, Mark Gurnell, Vivion Crowley et al. · Nature · 1999 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +12