Inhibition of leukotriene biosynthesis in mastocytoma cells by diethylcarbamazine

Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes

A. W. Ford‐Hutchinson, M.A. Bray, Mira Doig et al. · Nature · 1980 · 2.1K citations

Life Sciences, Cell Biology, Pharmacology +12

Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases

P Borgeat, Mats Hámberg, Bengt Samuelsson · Journal of Biological Chemistry · 1976 · 642 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +16

Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds.

P Borgeat, Bengt Samuelsson · Journal of Biological Chemistry · 1979 · 554 citations · Full text

Life Sciences, Biochemistry, Chromatographic Analysis +15

A new approach to anti-inflammatory drugs

G.A. Higgs, Roderick J. Flower, John R. Vane · Biochemical Pharmacology · 1979 · 503 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

RELEASE OF MEDIATORS OF ANAPHYLAXIS: INHIBITION OF PROSTAGLANDIN SYNTHESIS AND THE MODIFICATION OF RELEASE OF SLOW REACTING SUBSTANCE OF ANAPHYLAXIS AND HISTAMINE

D M Engineer, U Niederhauser, Priscilla J. Piper et al. · British Journal of Pharmacology · 1978 · 190 citations · Full text

Life Sciences, Immunology, Pharmacology +14