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Identification and optimisation of a series of substituted 5-pyridin-2-yl-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors

Medicinal ChemistryBiochemistryPotent Histone DeacetylaseMedicineNatural SciencesRational Drug DesignSubstituted 5-Pyridin-2-yl-thiophene-2-hydroxamic AcidsOrganic ChemistryPharmacotherapyAnti-cancer AgentDrug DevelopmentPharmacologyPharmaceutical ChemistryInhibitory ActivityDrug Discovery