Regulation of Neuronal Survival and Death by E2F-Dependent Gene Repression and Derepression

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

LA Greene, Arthur S. Tischler · Proceedings of the National Academy of Sciences · 1976 · 5.6K citations · Full text

Neural Stem Cell, Peripheral Nerves, Cellular Physiology +21

The E2F transcription factor is a cellular target for the RB protein

Srikumar Chellappan, Scott W. Hiebert, Maria Mudryj et al. · Cell · 1991 · 1.4K citations

Transcriptional Regulation, Signal Transduction, Cell Regulation +11

Functional Inactivation of the Retinoblastoma Protein Requires Sequential Modification by at Least Two Distinct Cyclin-cdk Complexes

Ante S. Lundberg, Robert A. Weinberg · Molecular and Cellular Biology · 1998 · 1.1K citations · Full text

Cdk Phosphorylation Triggers Sequential Intramolecular Interactions that Progressively Block Rb Functions as Cells Move through G1

J. William Harbour, Robin X Luo, Angeline Dei Santi et al. · Cell · 1999 · 1.1K citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +11

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

D. Gale Johnson, James K. Schwarz, W. Douglas Cress et al. · Nature · 1993 · 953 citations

Transcriptional Regulation, Systems Biology, Signal Transduction +14