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Acute toxicity, percutaneous absorption and effects on hepatic mixed function oxidase activities of 2,4,4?-trichloro-2?-hydroxydiphenyl ether (Irgasan� DP300) and its chlorinated derivatives

BiochemistryMedicineLiver PhysiologyToxicologyHepatotoxicityChlorinated DerivativesIrgasan� Dp300Toxicological AspectMetabolomicsExperimental ToxicologyPharmacologyDrug-induced Liver InjuryToxicological MechanismAcute ToxicityOxidative Stress