Degradation of uric acid during autocatalytic oxidation of oxyhemoglobin induced by sodium nitrite

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis.

B N Ames, Richard Cathcart, Elizabeth Schwiers et al. · Proceedings of the National Academy of Sciences · 1981 · 2.9K citations · Full text

Life Sciences, Biochemistry, Physiology +17

Iron promoters of the Fenton reaction and lipid peroxidation can be released from haemoglobin by peroxides

John M.C. Gutteridge · FEBS Letters · 1986 · 636 citations · Full text

Life Sciences, Biochemistry, Hematology +15

Uric acid-iron ion complexes. A new aspect of the antioxidant functions of uric acid

Kelvin J.A. Davies, Alex Sevanian, Samar F. Muakkassah-Kelly et al. · Biochemical Journal · 1986 · 559 citations · Full text

Life Sciences, Biochemistry, Bioenergetics +15

Formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Is haemoglobin a biological Fenton reagent?

Alain Puppo, Barry Halliwell · Biochemical Journal · 1988 · 401 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +16

The antioxidant activity of haptoglobin towards haemoglobin-stimulated lipid peroxidation

John M.C. Gutteridge · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1987 · 289 citations

Life Sciences, Biochemistry, Lipid Biochemistry +13