Poly(ethylene glycol) analogs grafted with low molecular weight poly(ethylene imine) as non-viral gene vectors

PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

Manfred Ogris, Silvia Brunner, Susanne Schüller et al. · Gene Therapy · 1999 · 1.2K citations

Pharmacy, Bioengineering, Pharmaceutics +16

Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle

W.T. Godbey, Kenneth K. Wu, Antonios G. Mikos · Journal of Biomedical Materials Research · 1999 · 822 citations

Pharmacy, Bioengineering, Biotechnology +16

PEGylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles

Swaroop Mishra, Paul Webster, Mark E. Davis · European Journal of Cell Biology · 2004 · 725 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +16

A Powerful Nonviral Vector for <i>In Vivo</i> Gene Transfer into the Adult Mammalian Brain: Polyethylenimine

Bassima Abdallah, Corinne Benoist, Daniel Goula et al. · Human Gene Therapy · 1996 · 542 citations

Life Sciences, Molecular Biology, Neuroscience +16

A Degradable Polyethylenimine Derivative with Low Toxicity for Highly Efficient Gene Delivery

M. Laird Forrest, James T. Koerber, Daniel W. Pack · Bioconjugate Chemistry · 2003 · 385 citations

Pharmacy, Bioengineering, Biotechnology +17