Stroke · 2011 · 227 citations · 16 references
Approximately 1 in 5 patients with stroke presenting within 3 hours received thrombolytic therapy. The onset-to-needle time, door-to-needle time, and especially imaging-to-needle time were significantly longer than those in developed countries. Reducing prehospital and in-emergency department response time would help increase intravenous rtPA use in China.
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Nils Wahlgren, Niaz Ahmed, Antoni Dávalos et al. · The Lancet · 2007 · 2.3K citations
Why are stroke patients excluded from TPA therapy?
P A Barber, Joyce L. Zhang, Andrew M. Demchuk et al. · Neurology · 2001 · 705 citations
Alteplase at 0.6 mg/kg for Acute Ischemic Stroke Within 3 Hours of Onset
Takenori Yamaguchi, Etsuro Mori, Kazuo Minematsu et al. · Stroke · 2006 · 508 citations · Full text