Arresting G-protein coupled receptor activity

β-Arrestin: a Protein that Regulates β-adrenergic Receptor Function

Martin J. Lohse, Jeffrey Benovic, Juan Codina et al. · Science · 1990 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +14

Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments.

Ursula Wilden, S W Hall, H. Kühn · Proceedings of the National Academy of Sciences · 1986 · 793 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.

Håvard Attramadal, J.L. Arriza, Chiye Aoki et al. · Journal of Biological Chemistry · 1992 · 549 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Experimental Allergic Uveitis. Isolation, Characterization, and Localization of a Soluble Uveitopathogenic Antigen from Bovine Retina

Waldon B. Wacker, Larry A. Donoso, Carolyn Μ. Kalsow et al. · The Journal of Immunology · 1977 · 520 citations

Medicine, Immunology, Ophthalmology +17

Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein).

Jeffrey Benovic, H. Kühn, Ingo Weyand et al. · Proceedings of the National Academy of Sciences · 1987 · 489 citations · Full text

Life Sciences, Biochemistry, Physiology +16