New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Pontus Boström, Jun Wu, Mark P. Jedrychowski et al. · Nature · 2012 · 4.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Mechanism of Hepatic Insulin Resistance in Non-alcoholic Fatty Liver Disease

Varman T. Samuel, Zhen Xiang Liu, Xianqin Qu et al. · Journal of Biological Chemistry · 2004 · 1.3K citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Prevalence of and Risk Factors for Nonalcoholic Fatty Liver Disease: The Dionysos Nutrition and Liver Study * #

Giorgio Bedogni, L. Miglioli, Flora Masutti et al. · Hepatology · 2005 · 1.3K citations · Full text

Medicine, Internal Medicine, Clinical Epidemiology +15

FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise

Joo Young Huh, Grigorios Panagiotou, Vassilis Mougios et al. · Metabolism · 2012 · 1K citations · Full text

Life Sciences, Biochemistry, Physiology +5

Irisin Is Expressed and Produced by Human Muscle and Adipose Tissue in Association With Obesity and Insulin Resistance

José María Moreno‐Navarrete, Francisco Ortega, Marta Serrano et al. · The Journal of Clinical Endocrinology & Metabolism · 2013 · 799 citations

Life Sciences, Endocrinology, Molecular Biology +15