Concepedia

IL-35 promotes pancreas cancer growth through enhancement of proliferation and inhibition of apoptosis: Evidence for a role as an autocrine growth factor

Michael B. Nicholl, Chelsea L. Ledgewood, Xuhui Chen, Qian Bai, Chenglu Qin, Kathryn M. Cook, Elizabeth J. Herrick, Alberto A. Diaz‐Arias, Bradley S. Moore, Yujiang Fang

Cytokine · 2014 · 75 citations · 33 references

DOI

Concepts

References

33

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

Lauren W. Collison, Creg J. Workman, Timothy Kuo et al. · Nature · 2007 · 2K citations

, , +12

Prevalence of Regulatory T Cells Is Increased in Peripheral Blood and Tumor Microenvironment of Patients with Pancreas or Breast Adenocarcinoma

Udaya Liyanage, Todd T. Moore, Hong‐Gu Joo et al. · The Journal of Immunology · 2002 · 1.5K citations

, , +13

IL-35-mediated induction of a potent regulatory T cell population

Lauren W. Collison, Vandana Chaturvedi, Abigail Henderson et al. · Nature Immunology · 2010 · 852 citations

, , +14

A dominant function for interleukin 27 in generating interleukin 10–producing anti-inflammatory T cells

Amit Awasthi, Yijun Carrier, Jean Pierre Schatzmann Peron et al. · Nature Immunology · 2007 · 802 citations

, , +17

The composition and signaling of the IL-35 receptor are unconventional

Lauren W. Collison, Greg M. Delgoffe, Clifford S. Guy et al. · Nature Immunology · 2012 · 447 citations · Full text

, , +11