Extracellular glutamate and other amino acids in experimental intracerebral hemorrhage: An in vivo microdialysis study

Abstract

The present study suggests that glutamate and other amino acids accumulate transiently in extracellular fluids in the perihematoma region during the early period of intracerebral hemorrhage. The exact role of these amino acids in the pathogenesis of neuronal injury observed in intracerebral hemorrhage needs to be defined.