A Toll-like receptor recognizes bacterial DNA

Hiroaki Hemmi, Osamu Takeuchi, Taro Kawai, +8

Nature

Toll-like ReceptorsVirulence FactorPathogenesisInnate Immune SystemToll-like Receptor +5

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Lena Alexopoulou, Agnieszka Czopik Holt, Ruslan Medzhitov, +1

Nature

InflammationToll-like ReceptorsMolecular ImmunologyCytokineAllergy +12

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

Fumitaka Hayashi, Kelly D. Smith, Adrian Ozinsky, +7

Nature

Host ResponseToll-like ReceptorsBacterial FlagellinAutoimmune DiseaseVirulence Factor +9

Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the <i>Lps</i> Gene Product

Katsuaki Hoshino, Osamu Takeuchi, Taro Kawai, +5

The Journal of Immunology

Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components

Osamu Takeuchi, Katsuaki Hoshino, Taro Kawai, +5

Immunity

Toll-like ReceptorsGram-negative BacteriologyVirulence FactorPathogenesisBacteriology +5

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors

Adrian Ozinsky, David M. Underhill, Jason D. Fontenot, +5

Proceedings of the National Academy of Sciences

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

Frank Mercurio, Hengyi Zhu, Brion W. Murray, +8

Science

ImmunologyMolecular BiologyInflammationSignaling PathwayCell Regulation +18

TRAF6 is a signal transducer for interleukin-1

Zhaodan Cao, Jessie Xiong, Masahiro Takeuchi, +2

Nature

InflammationCytokineSignal TransductionImmunologySignal Transducer +5

IRAK-M Is a Negative Regulator of Toll-like Receptor Signaling

Koichi S. Kobayashi, Lorraine D. Hernandez, Jorge E. Galán, +3

Cell

InflammationToll-like ReceptorsMolecular ImmunologySignal TransductionInnate Immune System +5

Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-β Promoter in the Toll-Like Receptor Signaling

Masahiro Yamamoto, Shintaro Sato, Kiyotoshi Mori, +4

The Journal of Immunology

Innate Immune SystemImmunologyToll-like ReceptorImmunologic MechanismInnate Immunity +17