THE REGULATORY EFFECT OF OESTROGENS ON FETAL GROWTH

Abstract

Summary. The effect of oestrogen on uterine and placental blood flow was studied in ovariectomized, progesterone-supplemented pregnant rabbits on Days 16 and 18 of gestation. The intravenous administration of 150 μg/kg conjugated equine oestrogens (Premarin) caused an increase in both myometrial and vaginal blood flows but a large decrease in the maternal placental flow. There was little change in total uterine blood flow and no change in intrauterine pressure.