6-Hydroxydopamine-Induced PC12 Cell Death is Mediated by MEF2D Down-regulation

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry et al. · Nature · 1995 · 4K citations

Protein Function, Biochemistry, Ice/ced-3 Protease +11

The Generation of Hydrogen Peroxide, Superoxide Radical, and Hydroxyl Radical by 6-Hydroxydopamine, Dialuric Acid, and Related Cytotoxic Agents

Gerald Cohen, Richard E. Heikkila, With the technical assistance of Dana MacNamee · Journal of Biological Chemistry · 1974 · 895 citations · Full text

Lipid Peroxidation, Superoxide Radical, Redox Biology +16

Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: A combined retrograde tracing and immunocytochemical study in the rat

H. Sauer, Wolfgang H. Oertel · Neuroscience · 1994 · 790 citations

Nigrostriatal Dopamine Neurons, Progressive Degeneration, Neurophysiology +11

Activity-Dependent Regulation of MEF2 Transcription Factors Suppresses Excitatory Synapse Number

Steven W. Flavell, Christopher W. Cowan, Tae-Kyung Kim et al. · Science · 2006 · 581 citations

Excitatory Synapse Number, Synaptic Transmission, Restrict Synapse Number +21

Neuronal Activity-Dependent Cell Survival Mediated by Transcription Factor MEF2

Zixu Mao, Azad Bonni, Fen Xia et al. · Science · 1999 · 512 citations

Synaptic Transmission, Cell Death, Cellular Neurobiology +19