Discovery of a potent atrial natriuretic peptide antagonist for ANPA receptors in the human neuroblastoma NB-OK-1 cell line

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.8K citations

Cent Inhibition, Inhibitory Activity, Biochemistry +8

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

Pamela J. Fraker, John C. Speck · Biochemical and Biophysical Research Communications · 1978 · 4.6K citations

Proteinlipid Interaction, Membrane Formation, Biochemistry +9

A membrane form of guanylate cyclase is an atrial natriuretic peptide receptor

Michael Chinkers, David L. Garbers, Ming‐Shi Chang et al. · Nature · 1989 · 1K citations

Molecular Pharmacology, Molecular Physiology, Signal Transduction +10

Physiological Role of Silent Receptors of Atrial Natriuretic Factor

Thomas Maack, Muneya Suzuki, Fernando Antônio de Almeida et al. · Science · 1987 · 940 citations

Selective Activation of the B Natriuretic Peptide Receptor by C-Type Natriuretic Peptide (CNP)

Kerry J. Koller, David Lowe, Gregory L. Bennett et al. · Science · 1991 · 730 citations

C-type Natriuretic Peptide, Fluid Homeostasis, Peptide Science +16