Neurology · 1966 · 134 citations · 0 references
MedicineBiomedical SciencesClinical SciencesGastroenterologyInflammationMitochondrial GeneticsBiomarker DevelopmentClinical TrialsGut HealthInflammatory BiomarkersInflammatory Bowel DiseaseBiomedical Research EthicsGastrointestinal Disease BiomarkersInflammatory Bowel Disease Activity AssessmentInflammatory Bowel Disease PathogenesisInflammatory Bowel Disease PathophysiologyInflammatory Bowel Disease TherapyIntestinal Health BiomarkersResearch Ethics Committees
<h3>Abstract</h3> The MUSIC study is a multi-centre, longitudinal study set in the real world IBD clinical setting to investigate and develop a new biomarker approach utilising mitochondrial DAMP and circulating DNA in assessing mucosal healing in Crohn’s disease. We present the study protocol (approved by East of Scotland Research Ethics Service, Scotland, United Kingdom - Reference No. 19/ES/0087) on 17<sup>th</sup> September 2019 and registered in ClinicalTrials.gov as NCT04760964 for this on-going project based in Scotland, UK.