Essential Role for the dsRNA-Dependent Protein Kinase PKR in Innate Immunity to Viral Infection

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

Xu Luo, I. Imawati Budihardjo, Hua Zou et al. · Cell · 1998 · 3.6K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

Heather P. Harding, Yuhong Zhang, David Ron · Nature · 1999 · 3.3K citations

Life Sciences, Biochemistry, Molecular Biology +10

Functional Role of Type I and Type II Interferons in Antiviral Defense

Ulrike Müller, Ulrich Steinhoff, Luiz F. L. Reis et al. · Science · 1994 · 2.5K citations · Full text

Life Sciences, Immunology, Host-pathogen Interactions +15

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

Matthew L. Albert, Birthe Sauter, Nina Bhardwaj · Nature · 1998 · 2.3K citations

Life Sciences, Cell Biology, Immunology +16