Concepedia

A Simple and Convenient One-Pot Synthesis of Benzimidazole Derivatives Using Cobalt(II) Chloride Hexahydrate as Catalyst

Abu T. Khan, Tasneem Parvin, Lokman H. Choudhury

Synthetic Communications · 2009 · 82 citations · 12 references

DOI

Abstract

Abstract A simple and efficient method for the convenient synthesis of 2-arylbenzimidazole has been described on reaction with o-phenylenediamine and various aromatic aldehydes using cobalt(II) chloride hexahydrate as a catalyst. The method is cost-effective, high-yielding, clean, and selective.

References

12

Mild and Highly Efficient Method for the Synthesis of 2-Arylbenzimidazoles and 2-Arylbenzothiazoles

Kiumars Bahrami, Mohammad Mehdi Khodaei, Fardin Naali · The Journal of Organic Chemistry · 2008 · 447 citations

An efficient and one-pot synthesis of imidazolines and benzimidazoles via anaerobic oxidation of carbon–nitrogen bonds in water

Pranjal Gogoi, Dilip Konwar · Tetrahedron Letters · 2005 · 232 citations

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Synthesis of some new 2-substituted-phenyl-1H-benzimidazole-5-carbonitriles and their potent activity against candida species

Hakan Göker, Canan Kuş, David W. Boykin et al. · Bioorganic & Medicinal Chemistry · 2002 · 226 citations

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A simple and efficient procedure for the synthesis of benzimidazoles using air as the oxidant

Songnian Lin, Lihu Yang · Tetrahedron Letters · 2005 · 211 citations

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A Simple and Efficient One-Pot Synthesis of 2-Substituted Benzimidazoles

Kiumars Bahrami, Mohammad Khodaei, Iman Kavianinia · Synthesis · 2007 · 193 citations

, , +7