Concepedia

Abstract

Until recently the clinical changes accompanying the evolution of Alzheimer’s disease have been relatively neglected (1,2). These clinical changes fall within two primary domains: cognitive and behavioral. The cognitive changes are directly or indirectly related to declining intellectual abilities and cortical functioning. They include changes in concentration and calculation abilities, memory abilities, orientation, language abilities, and functioning and self-care. Other changes, such as progressive gait disturbances and eventual loss of ambulatory ability, are also related to cognitive and cortical deterioration. Currently no treatment is capable f modifying the primary cognitive symptoms of Alzheimer’s disease (3,4). This paper focuses on the second domain of changes accompanying Alzheimer’s disease-behavioral changes. Although there is a paucity of information on the phe-

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