Development Growth & Differentiation · 1999 · 11 citations · 26 references
Molecular RegulationGeneticsGenomic MechanismDifferential Gene FunctionMolecular GeneticsOptogeneticsSensory SystemsCellular PhysiologySensory RaysSensory NeuroscienceSensory Organ DifferentiationStress‐induced PhenocopyStepwise RegulationHealth SciencesDevelopmental GeneticsMorphogenesisOrganogenesisGene ExpressionGene FunctionBiologyDevelopmental BiologyGene RegulationGenetic MechanismFunctional StepsCell Fate DeterminationSystems BiologyMedicine
The differentiation of male specific sensory rays in the nematode Caenorhabditis elegans is a complex process regulated by multiple genetic components. A novel approach with heat shock treatment was employed to show that multistep regulation is involved in this process. Intervention in this stepwise regulation resulted in phenocopy of specific gene mutations. The results suggest that differential gene function acting at a precise time frame is necessary to guide the normal differentiation of sensory rays.
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THE GENETICS OF <i>CAENORHABDITIS ELEGANS</i>
Sydney Brenner · Genetics · 1974 · 15.2K citations · Full text
Drosophila: A laboratory handbook
Trends in Ecology & Evolution · 1990 · 1.7K citations
MALE PHENOTYPES AND MATING EFFICIENCY IN <i>CAENORHABDITIS ELEGANS</i>
Jonathan Hodgkin · Genetics · 1983 · 294 citations · Full text