A letrozole-based dual aromatase–sulphatase inhibitor with in vivo activity

Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial

M Baum, Aman U. Budzar, J Cuzick et al. · The Lancet · 2002 · 2K citations

Pharmacy, Oncology, Pharmacotherapy +13

In Situ Estrogen Production via the Estrone Sulfatase Pathway in Breast Tumors: Relative Importance versus the Aromatase Pathway*

Steven J. Santner, Peter D. Feil, Richard J. Santen · The Journal of Clinical Endocrinology & Metabolism · 1984 · 406 citations

Life Sciences, Biochemistry, Oncology +17

Anastozole (A) is superior to tamoxifen (T) in treatment of postmenopausal (PM) women with early breast cancer (EBC) - First results of the ATAC (Arimidex, tamoxifen, alone or in combination) trial (on behalf of the ATAC Trialists' Group)

M Baum · UCL Discovery (University College London) · 2002 · 235 citations

Pharmacy, Oncology, Pharmacotherapy +17

Estrone sulfamates: potent inhibitors of estrone sulfatase with therapeutic potential

Nicola M. Howarth, Atul Purohit, Michael Reed et al. · Journal of Medicinal Chemistry · 1994 · 218 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates

LW Lawrence Woo, Atul Purohit, Bindu Malini et al. · Chemistry & Biology · 2000 · 155 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +14