Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

Peter C. Brooks, Anthony M.P. Montgomery, Mauricio Rosenfeld et al. · Cell · 1994 · 2.3K citations

Medicine, Cancer Biology, Oncology +16

Extensive Vasculogenesis, Angiogenesis, and Organogenesis Precede Lethality in Mice Lacking All αv Integrins

B. Bader, Helen Rayburn, Denise Crowley et al. · Cell · 1998 · 643 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Integrin αvβ3 Requirement for Sustained Mitogen-activated Protein Kinase Activity during Angiogenesis

Brian P. Eliceiri, Richard Klemke, Staffan Strömblad et al. · The Journal of Cell Biology · 1998 · 394 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis.

Staffan Strömblad, Jürgen C. Becker, Mayra Yebra et al. · Journal of Clinical Investigation · 1996 · 383 citations · Full text

Medicine, Cancer Biology, Oncology +17

Regulation of Tenascin-C, a Vascular Smooth Muscle Cell Survival Factor that Interacts with the αvβ3 Integrin to Promote Epidermal Growth Factor Receptor Phosphorylation and Growth

Peter Lloyd Jones, Julie Crack, Marlene Rabinovitch · The Journal of Cell Biology · 1997 · 349 citations · Full text

Life Sciences, Cell Biology, Pathology +13