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Publication | Open Access

The Hemorrhagic Coli Pilus (HCP) of Escherichia coli O157:H7 Is an Inducer of Proinflammatory Cytokine Secretion in Intestinal Epithelial Cells

DOIFull Paper Access

47

Citations

56

References

2010

Year

Maria A. Ledesma, Sara A. Ochoa, Ariadnna Cruz, Luz María Rocha-Ramírez, Jaime Mas‐Oliva, Carlos Eslava, Jorge A. Girón, Juan Xicohtencatl‐Cortés
PLoS ONE

Abstract

The HcpA pilin monomer of the HCP produced by EHEC O157:H7 is a potent inducer of IL-8 and TNF-alpha release, an event which could play a significant role in the pathogenesis of hemorrhagic colitis caused by this pathogen.

References

YearCitations

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