Concepedia

Activated ClpP kills persisters and eradicates a chronic biofilm infection

Brian P. Conlon, Ernesto Nakayasu, L Fleck, Michael D. LaFleur, Vincent M. Isabella, K. Coleman, Steve N. Leonard, Richard Smith, Joshua Adkins, Kim Lewis

Nature · 2013 · 671 citations · 41 references

DOI

Concepts

References

41

TREATMENT OF STAPHYLOCOCCAL INFECTIONS WITH PENICILLIN BY INTERMITTENT STERILISATION

JosephW. Bigger · The Lancet · 1944 · 1.2K citations

, , +9

Persister cells and tolerance to antimicrobials

Iris Keren, Niilo Kaldalu, Amy L. Spoering et al. · FEMS Microbiology Letters · 2003 · 1.1K citations

, , +17

Biofilms and Planktonic Cells of <i>Pseudomonas aeruginosa</i> Have Similar Resistance to Killing by Antimicrobials

Amy L. Spoering, Kim Lewis · Journal of Bacteriology · 2001 · 901 citations · Full text

, , +13

The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system

Susan Gottesman, Eric Roche, Yi Zhou et al. · Genes & Development · 1998 · 857 citations · Full text

, , +12

Specialized Persister Cells and the Mechanism of Multidrug Tolerance in <i>Escherichia coli</i>

Iris Keren, Devang Shah, Amy L. Spoering et al. · Journal of Bacteriology · 2004 · 855 citations

, , +16