Concepedia

PGC-1α Promotes Nitric Oxide Antioxidant Defenses and Inhibits FOXO Signaling Against Cardiac Cachexia in Mice

Tuoyu Geng, Ping Li, Xinhe Yin, Zhen Yan

American Journal Of Pathology · 2011 · 88 citations · 49 references

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49

Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy

Marco Sandri, Claudia Sandri, Alex Gilbert et al. · Cell · 2004 · 3K citations · Full text

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Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

Jiandie D. Lin, Paul T. Tarr, Chen-Yu Zhang et al. · Nature · 2002 · 2.5K citations

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Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators

Julie St‐Pierre, Stavit Drori, Marc Uldry et al. · Cell · 2006 · 2.2K citations · Full text

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The IGF-1/PI3K/Akt Pathway Prevents Expression of Muscle Atrophy-Induced Ubiquitin Ligases by Inhibiting FOXO Transcription Factors

Trevor N. Stitt, Doreen Drujan, Brian Clarke et al. · Molecular Cell · 2004 · 1.9K citations · Full text

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FoxO3 Coordinately Activates Protein Degradation by the Autophagic/Lysosomal and Proteasomal Pathways in Atrophying Muscle Cells

Jinghui Zhao, Jeffrey J. Brault, Andreas Schild et al. · Cell Metabolism · 2007 · 1.5K citations · Full text

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