3-Methoxalylchromones – versatile reagents for the regioselective synthesis of functionalized 2,4′-dihydroxybenzophenones, potential UV-filters

Abstract

The reaction of 1,3-bis-silyl enol ethers with 3-methoxalylchromones affords a great variety of functionalised 2,4'-dihydroxybenzophenones. These products are formed by a domino Michael/retro-Michael/Mukaiyama-aldol reaction. The synthesized compounds are promising candidates for the synthesis of the novel UV-A/B and UV-B filters.