British journal of surgery · 2008 · 140 citations · 31 references
MedicineSurgeryGastrointestinal OncologyGeneral SurgeryWound HealingColorectal SurgeryLaparoscopic SurgeryAbdominal AdhesionsElective ColectomyLaparoscopic Cancer SurgeryLaparoscopic Colorectal SurgeryLaparoscopic ResectionObservational Study EvaluationOpen ColectomyPostoperative Adhesion Formation
BACKGROUND: Adhesion formation is common after abdominal surgery. This study aimed to compare the extent of adhesion formation following laparoscopic and open colorectal surgery. METHODS: An observational study was undertaken to identify adhesions in patients undergoing laparoscopy after previous laparoscopic or open colectomy. Adhesions were scored according to a system validated for interobserver (median kappa = 0.80) and intraobserver (kappa = 0.82) agreement. The primary endpoint was the overall adhesion score (0-10); a secondary endpoint was the adhesion score at the main incision site (0-6). RESULTS: Forty-six patients were recruited (13 laparoscopic and 33 open colectomy). In most patients (n = 29), laparoscopy was performed for tumour staging before liver resection. The median (interquartile range) overall adhesion score was 7 (5-8) in the open group and 0 (0-3) in the laparoscopic group (P < 0.001). A similar difference was found for the main incision score: 6 (4-6) versus 0 (0-0) (P < 0.001). CONCLUSION: There may be a reduction in adhesion formation following laparoscopic compared with open colectomy, although the small sample size limits this conclusion.
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Practical Statistics for Medical Research.
Sophie Walter, Daniel Altman · Biometrics · 1992 · 11.7K citations
Intestinal obstruction from adhesions--how big is the problem?
D Menzies, Harold Ellis · PubMed · 1990 · 961 citations
Medicine, Surgery, Bowel Management +16