Synthesis of the pentacyclic intermediate for dynemicin a and unusual formation of spiro-oxindole ring

Crystal and molecular structure of dynemicin A: a novel 1,5-diyn-3-ene antitumor antibiotic

MASATAKA KONISHI, HIROAKI OHKUMA, Takashi Tsuno et al. · Journal of the American Chemical Society · 1990 · 444 citations

Medicine, Medicinal Chemistry, Pharmacology +9

Intramolecular alkene arylations for rapid assembly of polycyclic systems containing quaternary centers. A new synthesis of spirooxindoles and other fused and bridged ring systems

Matthew M. Abelman, Taeboem Oh, Larry E. Overman · The Journal of Organic Chemistry · 1987 · 329 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

Molecular design, chemical synthesis, and biological action of enediynes

K. C. Nicolaou, Adrian L. Smith · Accounts of Chemical Research · 1992 · 234 citations

Pharmacy, Chemistry, Medicinal Chemistry +7

Transannular Diels-Alder route to systems related to dynemicin A

John A. Porco, Frank J. Schoenen, Thomas J. Stout et al. · Journal of the American Chemical Society · 1990 · 175 citations

Natural Sciences, Chemistry, Analytical Chemistry +5

Tris(trimethylsilyl)silane as mediator in organic synthesis via radicals

Bernd Giese, B. Kopping, Chryssostomos Chatgilialoglu · Tetrahedron Letters · 1989 · 145 citations

Natural Sciences, Chemistry, Organic Chemistry +7