Archiv der Pharmazie · 1991 · 17 citations · 4 references
MedicineMedicinal ChemistryPharmacologyDrug DiscoveryNeuropharmacologyStructure-activity RelationshipsAnesthetic Drug PharmacologyAnesthetic PharmacologyHypnotic AgentsHypnotic TherapySedative-hypnotic PharmacologyStructure-activity Relationship AnalysisAmino Acid SubstitutionAmino Acid Substitution EffectsAnticonvulsant ActionAnticonvulsant DrugsHypnotic EffectsHypnotic MedicationsHypnotic PharmacologyThiazole Chemistry
Diverse biological activities have been found in compounds having a quinazolinone ring system. A large number of 4(3H)-quinazolinones, in particular those possessing 2-alkyl-3-aryl, 2,3-dialkyl, and 2-alkyl-3-amino substitution, have been evaluated for pharmacological activity. On the other hand, thiazolidone derivatives are reported to have anesthetic, anticonvulsant, and hypnotic activity.
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