Concepedia

Immobilization of Olefin Metathesis Catalysts on Monolithic Sol-Gel: Practical, Efficient, and Easily Recyclable Catalysts for Organic and Combinatorial Synthesis

Jason S. Kingsbury, Steven B. Garber, Jonathan M. Giftos, Brian L. Gray, Mariko M. Okamoto, Richard A. Farrer, John T. Fourkas, Amir H. Hoveyda

Angewandte Chemie International Edition · 2001 · 169 citations · 25 references

DOI

Concepts

Abstract

Glass-bound Ru-based catalysts! Ru-containing glass pellets efficiently promote olefin metathesis reactions and are easily employed in syntheses of compound libraries. These robust catalysts are active in air and commercially available solvents, can be recycled up to 16 times, and removed from reaction mixtures with a simple pair of tweezers (minimal solvent waste).

References

25

Synthesis and Activity of a New Generation of Ruthenium-Based Olefin Metathesis Catalysts Coordinated with 1,3-Dimesityl-4,5-dihydroimidazol-2-ylidene Ligands

Matthias Scholl, Sheng Ding, Choon Woo Lee et al. · Organic Letters · 1999 · 3.4K citations

, , +15

Recent advances in olefin metathesis and its application in organic synthesis

Robert H. Grubbs, Sukbok Chang · Tetrahedron · 1998 · 2.1K citations

, , +8

Synthesis and Applications of RuCl<sub>2</sub>(CHR‘)(PR<sub>3</sub>)<sub>2</sub>:  The Influence of the Alkylidene Moiety on Metathesis Activity

Peter Schwab, Robert H. Grubbs, Joseph W. Ziller · Journal of the American Chemical Society · 1996 · 2.1K citations

, , +16

Efficient and Recyclable Monomeric and Dendritic Ru-Based Metathesis Catalysts

Steven B. Garber, Jason S. Kingsbury, Brian L. Gray et al. · Journal of the American Chemical Society · 2000 · 2K citations

, , +17

A Series of Well‐Defined Metathesis Catalysts–Synthesis of [RuCl<sub>2</sub>(CHR′)(PR<sub>3</sub>)<sub>2</sub>] and Its Reactions

Peter Schwab, Marcia B. France, Joseph W. Ziller et al. · Angewandte Chemie International Edition in English · 1995 · 1.5K citations

, , +16