Interferon-gamma-induced dephosphorylation of STAT3 and apoptosis are dependent on the mTOR pathway

Stat3 as an Oncogene

Jacqueline Bromberg, Melissa H Wrzeszczynska, Geeta Devgan et al. · Cell · 1999 · 2.8K citations · Full text

Natural Sciences, Reactive Oxygen Specie, Molecular Biology +1

Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

Robyn Catlett-Falcone, Terry H. Landowski, Marc M. Oshiro et al. · Immunity · 1999 · 1.6K citations · Full text

Cell Regulation, Constitutive Activation, Medicine +8

Phosphorylation and Functional Inactivation of TSC2 by Erk

Li Ma, Zhenbang Chen, Hediye Erdjument‐Bromage et al. · Cell · 2005 · 1.3K citations · Full text

Signal Transduction, Signaling Pathway, Receptor Tyrosine Kinase +7

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

Jongkyeong Chung, Calvin J. Kuo, Gerald R. Crabtree et al. · Cell · 1992 · 1.2K citations

Signal Transduction, Signaling Pathway, Molecular Pathway +9

Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells.

Linda Mora, Ralf Buettner, John D. Seigne et al. · PubMed · 2002 · 536 citations

Apoptosis, Immunology, Cell Death +18