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One-pot three-component synthesis of functionalized spirolactones by means of reaction between aromatic ketones, dimethyl acetylenedicarboxylate, and N-heterocycles

EngineeringNatural SciencesDiversity-oriented SynthesisAromatic KetonesDimethyl AcetylenedicarboxylateOne-pot Three-component SynthesisOrganic ChemistryCatalysisChemistryHeterocycle ChemistryNatural Product SynthesisSynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering