Oxidative stress in Niemann–Pick disease, type C

Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol Homeostasis

Eugene D. Carstea, Jill A. Morris, Katherine Coleman et al. · Science · 1997 · 1.5K citations

Identification of <i>HE1</i> as the Second Gene of Niemann-Pick C Disease

Saule Naureckiene, David E. Sleat, Henry Lackland et al. · Science · 2000 · 827 citations

Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

Emyr Lloyd‐Evans, Anthony J. Morgan, Xingxuan He et al. · Nature Medicine · 2008 · 825 citations

Mendelian Disorder, Disease Mechanism, Genetic Disorder +10

Accumulation of Amyloid Precursor Protein in the Mitochondrial Import Channels of Human Alzheimer’s Disease Brain Is Associated with Mitochondrial Dysfunction

Latha Devi, Badanavalu M. Prabhu, Domenico F. Galati et al. · Journal of Neuroscience · 2006 · 780 citations · Full text

Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

Hyock Joo Kwon, Lina Abi-Mosleh, Michael Wang et al. · Cell · 2009 · 662 citations · Full text

Proteinlipid Interaction, Signal Transduction, Oxysterol +9