Design of a versatile linker for solid phase peptide synthesis: Synthesis of C-terminal primary/seconary amides and hydrazides

9-Fluorenylmethoxycarbonyl amino-protecting group

Louis A. Carpino, Grace Han · The Journal of Organic Chemistry · 1972 · 1K citations

Natural Sciences, Biochemistry, Chemistry +9

Solid-phase synthesis of protected peptide fragments using a trialkoxy-diphenyl-methylester resin.

H Rink · Tetrahedron Letters · 1987 · 856 citations

Natural Sciences, Biochemistry, Chemistry +7

Amino-acids and peptides. XXXIII. Nitrosyl chloride and butyl nitrite as reagents in peptide synthesis by the azide method; Suppression of amide formation

J. Honzl, J. Rudinger · Collection of Czechoslovak Chemical Communications · 1961 · 363 citations

Natural Sciences, Biochemistry, Chemistry +10

Solid Phase Synthesis (Nobel Lecture)

R. B. Merrifield · Angewandte Chemie International Edition in English · 1985 · 356 citations

Natural Sciences, Chemistry, Materials Chemistry +14

Preparation and application of the 5-(4-(9-fluorenylmethyloxycarbonyl)aminomethyl-3,5-dimethoxyphenoxy)-valeric acid (PAL) handle for the solid-phase synthesis of C-terminal peptide amides under mild conditions

Fernando Alberício, Nancy Kneib‐Cordonier, Sara Biancalana et al. · The Journal of Organic Chemistry · 1990 · 327 citations

Natural Sciences, Biochemistry, Chemistry +14