Polymyxin E : Penetration into the Eye and Therapeutic Value in Experimental Infection due to Ps. Pyocyanea

Abstract

THE polymyxins are a group of five closely allied antibiotics extracted from the Bacillus polymyxa. In vitro and in the field of general medicine they have been found bactericidal to nearly all Gram-negative bacilli, and the good results obtained in combating Ps. pyocyanea infection of burns by the local application of polymyxin (Jackson and others, 1951) suggested the possibility of using them locally in eye diseases.