Carbonic Anhydrase II Plays a Major Role in Osteoclast Differentiation and Bone Resorption by Effecting the Steady State Intracellular pH and Ca2+

Osteoclastic Bone Resorption by a Polarized Vacuolar Proton Pump

Harry C. Blair, Steven L. Teitelbaum, Robert W. Ghiselli et al. · Science · 1989 · 859 citations

Medicine, Biochemistry, Cell Biology +17

Carbonic anhydrase II deficiency identified as the primary defect in the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification.

William S. Sly, David Hewett‐Emmett, Michael P. Whyte et al. · Proceedings of the National Academy of Sciences · 1983 · 622 citations · Full text

Life Sciences, Biochemistry, Genetics +17

Resorption of bone by isolated rabbit osteoclasts

T.J. Chambers, Peter A. Revell, K. Fuller et al. · Journal of Cell Science · 1984 · 415 citations

Medicine, Animal Sciences, Bone Metabolism +10

Cellular Biology and Biochemical Mechanism of Bone Resorption

Gilbert Vaes · Clinical Orthopaedics and Related Research · 1988 · 403 citations

Medicine, Biochemistry, Cell Biology +17

Evidence for the presence of a proton pump of the vacuolar H(+)-ATPase type in the ruffled borders of osteoclasts.

H. Kalervo Väänänen, Eeva-Kaisa Karhukorpi, K. Sundquist et al. · The Journal of Cell Biology · 1990 · 391 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17