Concepedia

Synthesis and differential antiproliferative activity of Biginelli compounds against cancer cell lines: Monastrol, oxo-monastrol and oxygenated analogues

Dennis Russowsky, Rômulo Faria Santos Canto, Sérgio Augusto Antunes Sanches, Marcelo G. Montes D’Oca, Ângelo de Fátima, Ronaldo A. Pilli, Luciana K. Kohn, Márcia Aparecida Antônio, João Ernesto de Carvalho

Bioorganic Chemistry · 2006 · 208 citations · 33 references

DOI

Concepts

References

33

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.7K citations

Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

Thomas U. Mayer, Tarun M. Kapoor, Stephen J. Haggarty et al. · Science · 1999 · 1.7K citations

, , +18

100 years of the biginelli dihydropyrimidine synthesis

C. Oliver Kappe · Tetrahedron · 1993 · 1.2K citations

, , +3

Probing Spindle Assembly Mechanisms with Monastrol, a Small Molecule Inhibitor of the Mitotic Kinesin, Eg5

Tarun M. Kapoor, Thomas U. Mayer, Margaret Coughlin et al. · The Journal of Cell Biology · 2000 · 723 citations · Full text

Novel Alkaloids from the Sponge Batzella sp.: Inhibitors of HIV gp120-Human CD4 Binding

Ashok D. Patil, N. Vasant Kumar, W. C. M. C. Kokke et al. · The Journal of Organic Chemistry · 1995 · 602 citations

, , +21