Publication | Closed Access
Peroxisomes in the Rat Brain and the Effects of Di-(2-Ethylhexyl) Phthalate during Postnatal Development
13
Citations
0
References
1988
Year
Brain DevelopmentLipid PeroxidationPeroxisomal ProliferationSocial SciencesRat BrainEmbryologyOxidative StressNeurogenesisNeurochemistryAnimal PhysiologyDevelopmental ToxicologyCerebral CortexFetal NeurodevelopmentNervous SystemDevelopmental BiologyNeurophysiologyNeuroanatomyPhysiologyNeurosciencePostnatal DevelopmentMedicine
Peroxisomes were identified in the neurons of cerebral cortex of 12-day-old suckling rats from normal and plasticizer di-(2-ethylhexyl) phthalate (DEHP)-fed mothers. The study suggests that DEHP passed to the pups through the mother's milk during nursing can induce peroxisomal proliferation in neurons during postnatal development.