CYTOLYSOMES AND MITOCHONDRIAL DEGENERATION

Alex B. Novikoff, Edward Essner

The Journal of Cell Biology · 1962 · 262 citations · 8 references

DOIFull text

Open access

Concepts

Abstract

the pro:,imal convolutions of the kidneys of the newborn mouse, which contained mitochondria within them (7). Similar bodies have been found in cells of the proximal convolutions of rat kidney 6 hours following ligation of the ureter (14). These were identified with large acid phosphataserich bodies seen in frozen sections of cold formaldehyde-fixed tissue incubated in the glycerophosphate-lead medium of Gomori for acid phosphatase activity (10) and examined by light microscopy (14). Enlarged lysosomes have been encountered in acid phosphatase preparations of a variety of cells undergoing physiological and pathological lysis (14, 16, 3-5) and the term "cytolysome " has

References

8