Journal of Agricultural and Food Chemistry · 2008 · 42 citations · 11 references
Life SciencesChemistryEntomologyDrug DiscoveryInsect ToxicologyStructure-activity RelationshipsInsecticide ToxicityPesticide ChemistryBiological Activity FeaturesInsecticidal Activity AssaysInsecticide ChemistryNeonicotinoid PesticidesNuclear Magnetic Resonance StudiesSubstituent Effects On Biological ActivityThiazole ChemistryToxicity Bioassays
The N-substituted alkyl sulfoximine derivatives are a new chemical family of neonicotinoid insecticides. We have designed and synthesized 10 (1,3-thiazole)alkyl sulfoximine derivatives. All compounds were identified by (1)H and (13)C nuclear magnetic resonance (NMR), IR, and elemental analyses. Preliminary bioassays indicated that some title compounds exhibited good insecticidal activities at 10 mg/L against Myzus persicae . The relationship between structure and biological activity was also discussed.
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