Science · 1970 · 147 citations · 13 references
MedicineBehavioral SciencesPharmacologyBehavioral PharmacologyNeuropharmacologyPsychopharmacologyVeterinary NeuropharmacologyBehavioral PharmacodynamicsDisease-related Behavioral ChangesMedication-related Behavioral ChangesTryptophan HydroxylationTryptophan Metabolism
The behavior of 26 male cats was systematically observed before, during, and after daily administration of the tryptophan hydroxylase inhibitor, p-chlorophenylalanine. These observations established that "hypersexuality," increased aggression, and perceptual disorientation are sequelae of the chronic administration of the drug in cats.
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