Mechanical force activates eIF-2α phospho-kinases in fibroblast

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

Heather P. Harding, Yuhong Zhang, David Ron · Nature · 1999 · 3.2K citations

Protein Function, Signal Transduction, Protein Folding +6

Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

Thomas Dever, Lan Feng, Ronald C. Wek et al. · Cell · 1992 · 805 citations

Signal Transduction, Cell Regulation, Natural Sciences +12

Signal-Regulated Activation of Serum Response Factor Is Mediated by Changes in Actin Dynamics

Athanassia Sotiropoulos, Dziugas Gineitis, John W. Copeland et al. · Cell · 1999 · 655 citations · Full text

Signal Transduction, Signaling Pathway, Cell Interaction +11

The Compliance of Collagen Gels Regulates Transforming Growth Factor-β Induction of α-Smooth Muscle Actin in Fibroblasts

Pamela D. Arora, Nazanin Narani, Christopher A. McCulloch · American Journal Of Pathology · 1999 · 459 citations · Full text

Mechanobiology, Muscle Physiology, Developmental Biology +11

Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. Possible role of protein kinase C activation.

Issei Komuro, Youichi Katoh, T Kaida et al. · Journal of Biological Chemistry · 1991 · 436 citations · Full text

Cardiac Muscle, Muscle Function, Specific Gene Expression +21