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Grey variants of the live vaccine strain of Francisella tularensis lack lipopolysaccharide O-antigen, show reduced ability to survive in macrophages and do not induce protective immunity in mice

VaccinationMucosal VaccinationGrey VariantsVaccine DevelopmentPathogenesisImmunologyLive Vaccine StrainMicrobiologyInfection ControlVaccine DesignPolyvalent VaccineMedicineProtective Immunity