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Prophylactic effectiveness of live and killed tularemia vaccines. I. Production of vaccine and evaluation in the white mouse and guinea pig.
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1961
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Veterinary VaccineImmunologyVaccine SurveillanceSystematic EvaluationCell TransplantationVaccinologyVaccine SafetyWhite MouseStorage StabilityVaccine DevelopmentVaccine TestingTularemia VaccinesAutoimmunityVaccinationVeterinary ScienceVaccine DesignMedicineVaccine ResearchGuinea Pig
Data on the immunogenicity and storage stability of lyophilized live tularemia vaccine produced from cells harvested from GCHA and more recently from MCPH proved sufficiently encouraging to have warranted an extension of this study to a systematic evaluation of the vaccine in the monkey and subsequently in man.