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Delay of DNA-adduct repair and severe toxicity in xeroderma pigmentosum group A gene (XPA) deficient mice treated with 2-amino-1-methyl-6-phenyl-imidazo [4,5–b] pyridine (PhIP)

Deficient MiceGenome InstabilityDna DamageDna-adduct RepairPathologySevere ToxicityMutagenesisRadiation OncologyMedicineCell BiologyOxidative Stress